ADAM10 Rabbit Polyclonal Antibody

SKU AP05830PU-N

ADAM10 rabbit polyclonal antibody, Purified

Product Data

• Application: IF, WB
• Recommended Dilution: Western blot: 1/1000.; Immunocytochemistry.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide corresponding to amino acids 732-748 of Human CDw156C.
• Specificity: This antibody recognizes the C-terminal region of the meltalloprotease-disintegrin ADAM-10, also known as CDw156C.
• Buffer: PBS; State: Purified; State: Liquid purified IgG fraction; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: ADAM metallopeptidase domain 10
• Database Link:
  O14672
• Background: ADAM-10 is a member of the mammalian ADAM family and is involved in the cleavage of TNF alpha, Notch and its ligand delta. ADAM-10 mRNA is expressed in a variety of human tissues. Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM-10, CDw156, Mammalian disintegrin-metalloprotease, CD156c or Kuzbanian protein homolog. CD156c is a 748 amino acid ~85 kDa type I, single pass transmembrane glycoprotein with a 19 aa signal peptide and adjacent 194 aa propeptide region yeilding a mature 535 aa protease. CD156c is a member of the mammalian ADAM family and is involved in the cleavage of TNF alpha, Notch and its ligand delta (Primakoff & Miles 2000)
• Synonyms: KUZ, MADM, Kuzbanian protein homolog

Reference Data