CD5L (C-term) Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | Western blot: 0.5 - 1.0 µg/ml; detects a band of approximately 38kDa in Raji cell lysates. Immunohistochemistry on paraffin sections. |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | 13 amino acid peptide sequence near the carboxy terminus of human CD5L. |
| Specificity | This antibody detects an epitope within the C-terminal (CT) region of human CD5L. |
| Buffer | Phosphate buffered saline containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | CD5L is also known as Apoptosis Inhibitor expressed by Macrophages (AIM), and SP alpha. CD5L is a soluble 38kD glycoprotein which is specifically produced by mature macrophages, and has been shown to support their survival and enhance phagocytic function. CD5L expression is upregulated in response to LXR/RXR heterodimer activation. CD5L has been shown to mediate the survival of macrophages in atherosclerotic plaques. |
| Synonyms | SP-ALPHA |
| Reference Data | |
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