SAMD8 Rabbit Polyclonal Antibody

SKU AP05209PU-N

SAMD8 rabbit polyclonal antibody, Purified

Product Data

• Application: ELISA, WB
• Recommended Dilution: ELISA.; Western Blot: 5-10 µg/ml.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Full-length recombinant sphingomyelin synthase r fusion protein.
• Specificity: This antibody reacts to Sphingomyelin synthase-related protein 1.
• Buffer: Phosphate buffered saline with 0.08% Sodium Azide as preservative.; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: The antibody can be shipped at ambient temperature.; Store (in aliquots) at -20°C only.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: sterile alpha motif domain containing 8
• Database Link:
  Q96LT4
• Background: Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.
• Synonyms: FLJ25082; SMSr

Reference Data

• Protein Families: Transmembrane