Nlgn3 (730-848, Intracell. Dom.) Mouse Monoclonal Antibody [Clone ID: S110-29]
Product Data | |
Clone Name | S110-29 |
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Application | IF, IHC, WB |
Recommended Dilution | Western blot: 1/1000; 1 μg/ml was sufficient for detection of Neuroligin-3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using HRP conjugated secondary antibody. Immunocytochemistry. Immunohistochemistry: Free floating sections, fixed in formaldehyde. |
Reactivity | Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Fusion protein amino acids 730-848 (intracellular, C-terminus) of rat Neuroligin 3. |
Specificity | This antibody detects Neuroligin 3; ~110 kDa. Does not cross-react with Neuroligin-1, -2 or -4. |
Buffer | PBS pH 7.4, 50% Glycerol, 0.09% Sodium azide State: Purified State: Liquid purified IgG fraction |
Concentration | lot specific |
Purification | Protein G chromatography |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Shipping | Blue Ice |
Gene Name | neuroligin 3 |
Database Link | |
Background | Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. |
Synonyms | NLGN3, KIAA1480, NL3 |
Reference Data |
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