PARP2 Mouse Monoclonal Antibody [Clone ID: AT29G4]

SKU AM50055PU-S

PARP2 mouse monoclonal antibody, clone AT29G4, Purified

Product Data

• Clone Name: AT29G4
• Application: ELISA, FC, IF, WB
• Recommended Dilution: ELISA. ; Flow Cytometry ; Immunocytochemistry/Immunofluorescence.; Western blot / Immunoblot.; The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000. Recommended starting dilution is 1:500.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant human PARP2 (233-583aa) purified from E. coli
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: poly(ADP-ribose) polymerase 2
• Database Link:
  Q9UGN5
• Background: PARP2 is poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
• Synonyms: PARP-2, ADPRT2, ADPRTL2, Poly [ADP-ribose] polymerase 2, PARP 2, EC=2.4.2.30, pADPRT-2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair