MEMO1 Mouse Monoclonal Antibody [Clone ID: AT1E9]
| Product Data | |
| Clone Name | AT1E9 |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | ELISA. Western blot: 1/3000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant human MEMO1 (1-297aa) purified from E. coli |
| Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Protein-G affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | mediator of cell motility 1 |
| Database Link | |
| Background | MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity |
| Synonyms | C2orf4, NS5ATP7, CGI-27 |
| Reference Data | |
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