ARMET (MANF) Mouse Monoclonal Antibody [Clone ID: 1G12]
| Product Data | |
| Clone Name | 1G12 |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | ELISA: 1/32000. Western Blot: 1/2000-1/4000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human MANF produced using CHO-based. Antigen is purified from cell culture supernatant. |
| Specificity | Recognizes Human MANF. Other species not tested. |
| Buffer | PBS pH 7.4 State: Aff - Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | mesencephalic astrocyte derived neurotrophic factor |
| Database Link | |
| Background | MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson’s disease (Lindholm et al., 2008, Voutilainen et al., 2009). When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta. |
| Synonyms | Arginine-rich protein, MANF |
| Reference Data | |
Write Your Own Review
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.