DNA (double stranded) Mouse Monoclonal Antibody [Clone ID: AE-2]
| Product Data | |
| Clone Name | AE-2 |
|---|---|
| Application | IHC |
| Recommended Dilution | Immunohistochemistry on Frozen Sections: Use paraformaldehyde fixed or frozen tissue or cell preparations. Recommended Positive Control: Tonsil. Immunohistochemistry on Formalin Fixed, Paraffin-Embedded Tissue Sections. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG3 |
| Clonality | Monoclonal |
| Immunogen | A BALB/c mouse was immunized with nuclei of Raji Burkitt’s lymphoma cells. The isolated splenocytes were fused with mouse myeloma cells. |
| Specificity | This Monoclonal antibody AE-2 recognizes Double Stranded DNA expressed in the nucleus of Human cells. AE-2 produces a homogeneous staining pattern in the nucleus of normal and malignant cells. |
| Buffer | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.02% Sodium Azide |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs. |
| Synonyms | Deoxyribonucleic Acid |
| Reference Data | |
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