EMA (MUC1) Mouse Monoclonal Antibody [Clone ID: 139H2]

CAT#: AM32170PU-N

EMA (MUC1) mouse monoclonal antibody, clone 139H2, Purified

Product Images

Formalin-Fixed, Paraffin-Embedded Human Breast tissue respiratory epithelium stained with MUC1 Antibody Clone 139H2 at 10 ug/ml dilution after heat-induced antigen retrieval.

Specifications

Product Data

• Clone Name: 139H2
• Applications: ELISA, EM, FC, IF, IHC, IP, WB
• Recommended Dilution: ELISA.
  Western blot.
  Electron Microscopy.
  Flow Cytometry.
  Immunofluorescence.
  Immunoprecipitation.
  Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human milk-fat globule membranes (HMFGM).
• Specificity: This Mouse monoclonal antibody has been raised against Human milk-fat globule membranes (HMFGM) to obtain reagents for mammary tumor diagnosis.
  This monoclonal reacts towards an peptide epitope in the repeat region of MUC-1.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: mucin 1, cell surface associated
• Database Link:
  Entrez Gene 4582 Human
  UniProt ID P15941
• Background: Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs.
  The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity.
  Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers.
• Synonyms: MUC-1, PEMT, Episialin, EMA, H23AG, PUM, DF3, CA 15-3