Laminin gamma 1 (LAMC1) Mouse Monoclonal Antibody [Clone ID: BC17]

SKU AM32092PU-N

Laminin gamma 1 (LAMC1) mouse monoclonal antibody, clone BC17, Ig Fraction

Product Data

• Clone Name: BC17
• Application: ELISA, IHC, IP
• Recommended Dilution: ELISA. ; Immunoprecipitation.; Immunohistochemical on Frozen Sections. ; Does not work in Western blotting.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Pepsin-digested laminins from Human placenta.; Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
• Specificity: The antibody recognizes the Mr 200,000 gamma-1-chain of Human reduced and Alkylated Laminin produced by various cultured cells, which produce Laminins complexed with it.; The specificity of Mab BC17 has been confirmed by Immunoprecipitation and ELISA by using recombinant gamma-1- chain. ; The antibody only reacts with Human cells and tissues (further studies are going on).
• Buffer: PBS; State: Ig Fraction; State: Liquid Ig fraction; Stabilizer: 1.0% BSA; Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.;
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: laminin subunit gamma 1
• Database Link:
  P11047
• Background:
  Laminin, a major structural glycoprotein of the basement membranes, is an attachment and survival factor for epithelial cells and can also promote the growth of epithelial cells.
  ; Laminin plays an important role in both the structural organization of basement membranes and in the anchorage of cells. The monoclonal antibody, DG10 and BC17 against laminin chain ß1 and γ1, respectively can be widely applied in immunohistochemical studies as all basement membranes contain laminin trimers containing these chains. Antibodies to laminin chains are useful in basic biology studies as well as in pathological studies concerning, for instance, the integrity of the basement membranes in carcinomas.
• Synonyms: LAMC1, LAMB2, Laminin subunit gamma-1, Laminin B2 chain

Reference Data