PRUNE (PRUNE1) Mouse Monoclonal Antibody [Clone ID: 1C11]

SKU AM31933PU-N

PRUNE (PRUNE1) mouse monoclonal antibody, clone 1C11, Purified

Product Data

• Clone Name: 1C11
• Application: ELISA, IHC, WB
• Recommended Dilution: ELISA.; Immunohistochemistry on Paraffin Sections: 5 µg/ml.; Western Blot.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant protein
• Specificity: This antibody recognizes Human PRUNE.
• Buffer: PBS, pH 7.2; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: prune exopolyphosphatase
• Database Link:
  Q86TP1
• Background: PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.
• Synonyms: Protein prune homolog, hPrune, HTcD37, DRES17, DRES-17

Reference Data

• Protein Pathways: Purine metabolism