Emilin1 Rat Monoclonal Antibody [Clone ID: C11A8]

SKU AM31889PU-N

Emilin1 rat monoclonal antibody, clone C11A8, Purified

Product Data

• Clone Name: C11A8
• Application: IF, IHC, WB
• Recommended Dilution: Western Blot: 2-10 µg/ml. ; Immunofluorescence.; Immunohistochemistry on Frozen Sections.
• Reactivity: Mouse
• Antibody Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant Mouse Emilin-1
• Specificity: This antibody was selected for its ability to detect Murine Emilin-1.
• Buffer: PBS; State: Purified; State: Lyophilized (0.2 μm filtered) purified IgG fraction
• Reconstitution Method: Restore in sterile water to a concentration is 0.1-1.0 mg/ml. Centrifuge vial prior to opening.
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C for one month or at -20°C for longer. ; Following reconstitution store undiluted at 2-8°C for one month ; or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient
• Gene Name: elastin microfibril interfacer 1
• Database Link:
  Q99K41
• Background: Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.
• Synonyms: EMILIN-1, EMI

Reference Data