BCL3 Hamster Monoclonal Antibody [Clone ID: Ham150-3.5]

SKU AM31856FC-N

BCL3 hamster monoclonal antibody, clone Ham150-3.5, FITC

Product Data

• Clone Name: Ham150-3.5
• Application: FC
• Recommended Dilution: This Clone has been described to work in ELISA, Western Blot and Flow Cytometry.
• Reactivity: Human, Mouse
• Antibody Host: Hamster
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Bcl-3-6-Histidine tag.; Donor: Armenia Hamster.; Fusion Partner: SP2/0 myeloma.
• Specificity: Recognizes B-cell Leukemia/lymphoma 3 (Bcl-3).
• Buffer: PBS containing 0.02% Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.; Label: FITC; State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Protein G Affinity Chromatography
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; This product is photosensitive and should be protected from light.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: B-cell CLL/lymphoma 3
• Database Link:
  P20749
• Background: B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells.; Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. The Mouse Bcl-3 coding region exhibits 80% homology with Human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs).; Bcl-3 is detected in various tissues such as spleen and other lymphoid organs.
• Synonyms: BCL3, BCL4, D19S37

Reference Data

• Protein Families: Druggable Genome, Transcription Factors