IL13 receptor alpha 2 (IL13RA2) Mouse Monoclonal Antibody [Clone ID: B-D13]
Product Data | |
Clone Name | B-D13 |
---|---|
Application | FC, IHC |
Recommended Dilution | Flow Cytometry. Immunohistochemistry on Paraffin Embedded Sections. Immunohistochemistry on Frozen Sections and methanol fixed cells. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | IL-13Ra2 transfected CHO cell line. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells. |
Specificity | Recognizes the soluble antigen. Recognizes the IL-13 receptor a2 (IL-13 Ra2), a 44 kDa protein. |
Buffer | Phosphate-buffered saline without carrier and preservatives. This prodcut is sterile-filtered through 0.22 µm and treated to remove endotoxins. State: Azide Free State: Liquid purified IgG fraction |
Concentration | lot specific |
Purification | Ion Exchange Chromatography |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | interleukin 13 receptor subunit alpha 2 |
Database Link | |
Background | IL-13 receptor alpha 2 belongs to the type I cytokine receptor family; Contains 1 fibronectin type-III domain; Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation. |
Synonyms | Interleukin-13 receptor alpha-2 chain, IL13RA2, IL-13RA-2, IL13R, IL13 receptor alpha-2, IL-13R-alpha-2 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Jak-STAT signaling pathway |
Write Your Own Review
Product Manuals |
FAQs |
SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.