Alkyl DHAP synthase (AGPS) (158-384) Mouse Monoclonal Antibody [Clone ID: AGPS-03]

SKU AM26765PU-N

Alkyl DHAP synthase (AGPS) (158-384) mouse monoclonal antibody, clone AGPS-03, Purified

Product Data

• Clone Name: AGPS-03
• Application: FC, WB
• Recommended Dilution: Flow cytometry: 1-4 µg/ml. Intracellular staining.; Western blot: 1-2 µg/ml.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant human AGPS (amino acids 158-384)
• Specificity: This antibody recognizes AGPS (alkykglycerone phosphate synthase), an peroxisomal enzyme important for lipid biosynthesis.
• Buffer: Phosphate buffered saline (PBS); State: Purified; State: Liquid Ig fraction; Preservative: 15 mM sodium azide, approx. pH 7.4
• Concentration: lot specific
• Purification: Protein-A affinity chromatography (>95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.; DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: alkylglycerone phosphate synthase
• Database Link:
  O00116
• Background: AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
• Synonyms: Alkyl-DHAP synthase

Reference Data