LILRB1 Mouse Monoclonal Antibody [Clone ID: GHI/75]

SKU AM26748PU-N

LILRB1 mouse monoclonal antibody, clone GHI/75, Purified

Product Data

• Clone Name: GHI/75
• Application: FC, FN, IP, WB
• Recommended Dilution: Flow cytometry.; Immunoprecipitation.; Western blot.; Functional application: blocking HLA-G induced TGF-beta1 production.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Hairy cell leukaemia cells
• Specificity: This antibody recognizes CD85j / ILT2, an 110-120 kDa membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells, and weakly on monocytes. It is also expressed on T cell and NK cell subsets (variable, individual).
• Buffer: Phosphate buffered saline (PBS); State: Purified; State: Liquid Ig fraction; Preservative: 15 mM sodium azide, approx. pH 7.4
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.; DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: leukocyte immunoglobulin like receptor B1
• Database Link:
  Q8NHL6
• Background: CD85j, also known as ILT-2 (Ig-like transcript 2), LIR-1 (leukocyte Ig-like receptor 1), or LILRB1 (leukocyte Ig-like receptor B1), is a member of Ig superfamily transmembrane glycoproteins named CD85. The CD85j protein is expressed on several types of immune cells (plasma cells, B cells, monocytes, T and NK cell subsets) where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
• Synonyms: LILR-B1, ILT2, LIR1, MIR7, LIR-1, ILT-2, MIR-7

Reference Data