CCR2 Mouse Monoclonal Antibody [Clone ID: 7A7]

SKU AM26722PU-N

CCR2 mouse monoclonal antibody, clone 7A7, Purified

Product Data

• Clone Name: 7A7
• Application: IHC
• Recommended Dilution: Immunohistochemistry on paraffin sections: 10-20 µg/ml (1/40-1/20). Pretreatment with proteinase K required.; Immunohistochemistry on frozen tissues: 4-8 µg/ml (1/100 - 1/50).; Human tonsil is suggested as positive control tissue.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: DNA vaccine
• Specificity: This antibody detects Human CCR2B.
• Buffer: Phosphate buffered saline pH 7.2 (PBS); State: Purified; State: Lyophilized affinity purified Ig fraction; Stabilizer: 5 mg/ml BSA; Preservative: 0.1% Kathon
• Reconstitution Method: Restore by adding 0.5 ml distilled water
• Concentration: 0.4 mg/ml IgG (after reconstitution)
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 month or at -20°C long term.; After reconstitution store the antibody undiluted at 2-8°C for one month ; or (in aliquots) at -20°C long term.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient
• Gene Name: C-C motif chemokine receptor 2
• Database Link:
  P41597
• Background: CCR2B is a 374 amino acid protein that belongs to the G - protein coupled receptor 1 family with seven transmembrane domains. It mediates the chemotactic properties of monocyte chemoattractant protein 1 (MCP - 1) which is secreted by endothelial and epithelial cells, vascular smooth muscle and hematopoietic cells. MCP - 1 is a potent chemoattractant for monocytes and lymphocytes. It is responsible for monocyte infiltration in a variety of chronic inflammatory diseases.
• Synonyms: C-C CKR-2, CC-CKR-2, CCR-2, CMKBR2

Reference Data