Mx1 Mouse Monoclonal Antibody [Clone ID: AM39]
Product Data | |
Clone Name | AM39 |
---|---|
Application | ELISA, WB |
Recommended Dilution | ELISA. Western blot. |
Reactivity | Bovine, Porcine |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant Porcine Mx1 protein |
Specificity | This Monoclonal antibody AM39 recognizes the Porcine Mx1 protein. |
Buffer | Stock solution contains PBS, pH 7.2 with 5 mg/ml BSA as a stabilizer and 0.09% Sodium Azide as a preservative State: Aff - Purified State: Lyophilized purified Ig fraction |
Reconstitution Method | Restore by adding 0.5 ml distilled water. |
Concentration | 0.4 mg/ml (after reconstitution) |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Background | Mx proteins are cytoplasmic proteins induced by type-1 interferons (α and β) in leukocytes. However, there is a baseline level of expression even in the absence of viral infection. In humans, mainly monocytes and lymphocytes have been shown to express the Mx gene, whereas Mx expression is low in granulocytes. Mx proteins are high molecular weight GTPases of 70 - 80kD which belong to the dynamin superfamily. Mx proteins have a strong propensity to aggregate and form homooligomers. A unique property is their antiviral activity against many RNA viruses. |
Synonyms | Mx1 protein |
Reference Data |
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