HLA II Mouse Monoclonal Antibody [Clone ID: HKB1]

SKU AM26128PU-N

HLA II mouse monoclonal antibody, clone HKB1, Aff - Purified

Product Data

• Clone Name: HKB1
• Application: FC, IHC
• Recommended Dilution: Immunohistochemistry on Frozen Sections: 1 µg/ml (1/400).; Has been described to work in FACS.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: REH cells, a Human B cell precursor leukemia cell line.
• Specificity: This antibody recognizes all HLA class II antigens, the 3 major (HLA-DP, -DQ and -DR) and 2 minor Major Histocompatibility Complex MHC class II proteins (HLA-DM and -DO).
• Buffer: Stock solution contains PBS, pH 7.2 with 5 mg/ml BSA as a stabilizer and 0.09% Sodium Azide as preservative.; State: Aff - Purified; State: Lyophilized purified Ig fraction
• Reconstitution Method: Restore by adding 0.5ml distilled water.
• Concentration: 0.4 mg/ml
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C.; Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient
• Background: The genes of the class II combine to form heterodimeric (αβ) protein receptors that are typically expressed on the surface of antigen presenting cells (APCs): dendritic cells B-cells and macrophages. HLA class II is presented on acticvated T-cells. HLA class II molecules present exogenously derived antigen to the T cell receptor (TCR) on CD4+ T lymphocytes.
• Synonyms: HLA ll, human leukocyte antigen class ll

Reference Data