Laminin alpha 5 (LAMA5) Mouse Monoclonal Antibody [Clone ID: 4B12]

CAT#: AM26110PU-N

Laminin alpha 5 (LAMA5) mouse monoclonal antibody, clone 4B12, Purified

Product Images

Reactivity of Laminin alpha-5 chain specific monoclonal antibody 4B12 on Human embryonic lung alveolae epithelium (A) and kidney (B) preparation.

Specifications

Product Data

• Clone Name: 4B12
• Applications: ELISA, IF, IHC, IP
• Recommended Dilution: ELISA: 1/8000.
  Immunoprecipitation: 1/20.
  Immunohistochemistry: 1/100–1/200.
  This antibody does Not work in Western blot!
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Laminin purified from Human placenta (Chemicon)
• Specificity: This antibody detects Laminin alpha 5.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatorgaphy on Protein G
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: laminin subunit alpha 5
• Database Link:
  Entrez Gene 3911 Human
  UniProt ID O15230
• Background: Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cellsurface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination, laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their > chain, are expressed in a cell- and tissue-specific manner, and are differentially recognized by integrins.
• Synonyms: LAMA5, KIAA0533, KIAA1907, Laminin subunit alpha-5

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer