Laminin alpha 5 (LAMA5) Mouse Monoclonal Antibody [Clone ID: 4B12]
Product Data | |
Clone Name | 4B12 |
---|---|
Application | ELISA, IF, IHC, IP |
Recommended Dilution | ELISA: 1/8000. Immunoprecipitation: 1/20. Immunohistochemistry: 1/100–1/200. This antibody does Not work in Western blot! |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Laminin purified from Human placenta (Chemicon) |
Specificity | This antibody detects Laminin alpha 5. |
Buffer | PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatorgaphy on Protein G |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | laminin subunit alpha 5 |
Database Link | |
Background | Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cellsurface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination, laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their > chain, are expressed in a cell- and tissue-specific manner, and are differentially recognized by integrins. |
Synonyms | LAMA5, KIAA0533, KIAA1907, Laminin subunit alpha-5 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer |
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