Frataxin (FXN) Mouse Monoclonal Antibody [Clone ID: 2FRA-1G2]
Product Data | |
Clone Name | 2FRA-1G2 |
---|---|
Application | IHC |
Recommended Dilution | Immunohistochemistry on Frozen Sections: Not tested. Immunohistochemistry on Paraffin Sections: 20 µg/ml (1/10). Proteinase K pretreatment for antigen retrieval recommended. Suggested Positive Control: Swine brain cortex. |
Reactivity | Human, Porcine |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | TrpE-Frataxin full length. |
Specificity | This Monoclonal antibody Clone 2FRA-1G2 recognizes Human Frataxin. Frataxin is localized to the mitochondrion. Antigen Distribution: The antigen has been described in the heart, peripheral blood lymphocytes and dermal fibroblasts. |
Buffer | Stock solution contains PBS, pH 7.2 with 5mg/ml BSA as stabilizer and 0.01% Kathon as a preservative State: Aff - Purified State: Lyophilized purified IgG fraction |
Reconstitution Method | Restore by adding 0.5 ml distilled water |
Concentration | 0.5 mg/ml (after reconstitution) |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Gene Name | frataxin |
Database Link | |
Background | The function of frataxin is not entirely clear, but it seems to be involved in assembly of iron-sulfur clusters. It has been proposed to act as either an iron chaperone or an iron storage protein. |
Synonyms | Frataxin mitochondrial, FRDA, Friedreich ataxia protein |
Reference Data | |
Protein Families | Druggable Genome |
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