alpha 1 Spectrin (SPTA1) Mouse Monoclonal Antibody [Clone ID: Spe 1/2]
Product Data | |
Clone Name | Spe 1/2 |
---|---|
Application | WB |
Recommended Dilution | Western Blot: 2 - 4 μg/ml. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human erythrocyte spectrin |
Specificity | This antibody reacts to Spectrin (erythrocyte) (alpha / beta). |
Buffer | 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction |
Reconstitution Method | Restore with 1.2% sodium acetate or neutral PBS |
Concentration | 0,1 mg/ml (after reconstitution with PBS) |
Purification | Affinity chromatography |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Gene Name | spectrin alpha, erythrocytic 1 |
Database Link | |
Background | Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2.Spectrin mutations cause spinocerebellar ataxia type 5. |
Synonyms | SPTA, Erythroid alpha-spectrin |
Reference Data |
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