CD1 (CD1D) Mouse Monoclonal Antibody [Clone ID: 51.1]

SKU AM20466PU-N

CD1 (CD1D) mouse monoclonal antibody, clone 51.1, Aff - Purified

Product Data

• Clone Name: 51.1
• Application: FC, IHC
• Recommended Dilution: Flow Cytometry.; Immunohistochemistry on Frozen Sections.; Immunohistochemistry on Paraffin Sections: 20 µg/ml.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human CD1d
• Specificity: The monoclonal antibody reacts with Human CD1d.
• Buffer: PBS, pH 7.2 containing < / = 0.09% Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody at 2-8°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: CD1d molecule
• Database Link:
  P15813
• Background: Human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.
• Synonyms: R3G1

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage