GM CSF Receptor alpha (CSF2RA) Mouse Monoclonal Antibody [Clone ID: 4H1]

CAT#: AM20017PU-N

GM CSF Receptor alpha (CSF2RA) mouse monoclonal antibody, clone 4H1, Purified

Product Images

Surface staining (mass cytometry) of human peripheral blood with anti-CD116 (4H1) 153Eu. Gated on singlets.

Specifications

Product Data

• Clone Name: 4H1
• Applications: FC, IHC, IP, WB
• Recommended Dilution:
  Flow Cytometry.

  Immunoprecipitation.

  Western blot.

  Immunohistochemistry on Frozen Sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CD116-transfected COS cells
• Specificity: This antibody recognizes Human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.
• Formulation: Tris buffered saline (TBS), pH~8.0
  State: Purified
  State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: colony stimulating factor 2 receptor alpha subunit
• Database Link:
  Entrez Gene 1438 Human
  UniProt ID P15509
• Background: CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5 receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.
• Synonyms: GM-CSF-R-alpha, GMR, CSF2R, CSF2RY, GMCSF Receptor alpha, GM-CSF Receptor alpha