GM CSF Receptor alpha (CSF2RA) Mouse Monoclonal Antibody [Clone ID: 4H1]
Product Data | |
Clone Name | 4H1 |
---|---|
Application | FC, IHC, IP, WB |
Recommended Dilution | Flow Cytometry.
Immunoprecipitation.
Western blot.
Immunohistochemistry on Frozen Sections.
|
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | CD116-transfected COS cells |
Specificity | This antibody recognizes Human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages. |
Buffer | Tris buffered saline (TBS), pH~8.0 State: Purified State: Liquid purified Ig fraction (> 95% by SDS-PAGE) Preservative: 15 mM Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | colony stimulating factor 2 receptor alpha subunit |
Database Link | |
Background | CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5 receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias. |
Synonyms | GM-CSF-R-alpha, GMR, CSF2R, CSF2RY, GMCSF Receptor alpha, GM-CSF Receptor alpha |
Reference Data |
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