TUBB2B Mouse Monoclonal Antibody [Clone ID: AT5B3]

SKU AM09375PU-S

TUBB2B mouse monoclonal antibody, clone AT5B3, Purified

Product Data

• Clone Name: AT5B3
• Application: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.; Western blot: 1/250-1/500.; Immunofluorescence: 1/250-1/500.; Immunohistochemistry on Paraffin Embedded tissues: 1/50.
• Reactivity: Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant Human TUBB2b (1-445aa) purified from E. coli.
• Specificity: The antibody recognizes Human and Mouse TUBB2B. Other species not tested.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: tubulin beta 2B class IIb
• Database Link:
  Q9BVA1
• Background: The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. Multiple beta Tubulin isoforms have been characterized and are expressed in mammalian tissues. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2b is mainly expressed in developing neurons with a dominant expression during the critical steps of corticogenesis. Also, TUBB2B is a new critical gene involved in neuronal migration. It is present in the nuclei and nucleoplasm, Defects in this gene are a cause of asymmetric polymicrogyria.
• Synonyms: Tubulin beta-2B chain, beta II Tubulin B, beta-Tubulin, RP11-506K6.1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Gap junction, Pathogenic Escherichia coli infection