Bak (BAK1) Mouse Monoclonal Antibody [Clone ID: AT8B4]

CAT#: AM09369PU-S

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Bak (BAK1) mouse monoclonal antibody, clone AT8B4, Purified

USD 313.00

3 Weeks

    • 50 ul

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Product Data
Clone Name AT8B4
Applications ELISA, FC, IF, WB
Recommended Dilution ELISA.
Western blot: 1/250-1/500. 
Flow Cytometry.
Immunofluorescence: 1/250-1/500.
Reactivities Human, Mouse
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant Human BAK1 (29-187aa) purified from E. coli
Specificity The antibody recognizes Human and Mouse BAK1. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G Affinity Chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens BCL2 antagonist/killer 1 (BAK1)
Background BAK1 encodes an receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtamembrane domain, and a kinase domain. BAK1 expression is associated with the progression of Prostate cancer (CaP). BAK1 appears to function in distinct receptor-signaling complexes to integrate multiple microbe-associated molecular pattern (MAMP) perception into downstream-signaling events. BAK1 can serve multiple purposes to simultaneously modulate MAMP-receptor complexes, BR signaling, and cell death for the benefit of bacterial infection, life style, and fitness.
Synonyms BAK1, BAK, BCL2L7, Bcl2-L-7, CDN1
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transmembrane
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