Bak (BAK1) Mouse Monoclonal Antibody [Clone ID: AT8B4]

SKU AM09369PU-S

Bak (BAK1) mouse monoclonal antibody, clone AT8B4, Purified

Product Data

• Clone Name: AT8B4
• Application: ELISA, FC, IF, WB
• Recommended Dilution: ELISA.; Western blot: 1/250-1/500. ; Flow Cytometry.; Immunocytochemistry/Immunofluorescence.; Immunofluorescence: 1/250-1/500.
• Reactivity: Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant Human BAK1 (29-187aa) purified from E. coli
• Specificity: The antibody recognizes Human and Mouse BAK1. Other species not tested.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: BCL2 antagonist/killer 1
• Database Link:
  Q16611
• Background: BAK1 encodes an receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtamembrane domain, and a kinase domain. BAK1 expression is associated with the progression of Prostate cancer (CaP). BAK1 appears to function in distinct receptor-signaling complexes to integrate multiple microbe-associated molecular pattern (MAMP) perception into downstream-signaling events. BAK1 can serve multiple purposes to simultaneously modulate MAMP-receptor complexes, BR signaling, and cell death for the benefit of bacterial infection, life style, and fitness.
• Synonyms: BAK1, BAK, BCL2L7, Bcl2-L-7, CDN1

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transmembrane