KCTD15 Mouse Monoclonal Antibody [Clone ID: AT4C3]
Product Data | |
Clone Name | AT4C3 |
---|---|
Application | ELISA, FC, IF, WB |
Recommended Dilution | ELISA. Western blot (1:250 - 1:1000). Flow Cytometry. Immunofluorescence (1:250 - 1:500). |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG3 |
Clonality | Monoclonal |
Immunogen | Recombinant human KCTD15 (1-234aa) purified from E. coli |
Specificity | The antibody recognizes human KCTD15. Other species not tested. |
Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein-G affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | potassium channel tetramerization domain containing 15 |
Database Link | |
Background | KCTD15 (Potassium channel tetramerisation domain containing 15, also known as BTB/POZ domain-containing protein KCTD15) is protein that in humans is encoded by the KCTD15 gene. KCTD15 is expressed at high level in brain and hypothalamus. The potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels. |
Synonyms | KCTD15, KCTD-15, BTB/POZ domain-containing protein KCTD15 |
Reference Data | |
Protein Families | Ion Channels: Other |
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