Glucose 6 Phosphate Dehydrogenase (G6PD) (35-506) Mouse Monoclonal Antibody [Clone ID: AT2F6]
Specifications
| Product Data | |
| Clone Name | AT2F6 |
|---|---|
| Application | ELISA, FC, ICC/IF, IF, IHC, WB |
| Recommended Dilution | ELISA. Western blot (1:1,000 - 1:2,000). Immunohistochemistry on Paraffin sections (5 µg/ml). Immunocytochemistry / Immunoflourescence. Flow cytometry. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b, kappa |
| Clonality | Monoclonal |
| Immunogen | Recombinant human G6PD (35-506aa) purified from E. coli |
| Specificity | The antibody recognizes human G6PD at aa 35-506. Other species not tested. |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purification | By protein-G affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | glucose-6-phosphate dehydrogenase |
| Database Link | |
| Background | Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone and simultaneously produce NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency cause acute hemolytic anemia. |
| Synonyms | glucose-6-phosphate 1-dehydrogenase, G6PD1, G6PDH |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins |
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