BID (1-195) Mouse Monoclonal Antibody [Clone ID: 4D3]

SKU AM09052PU-N

BID (1-195) mouse monoclonal antibody, clone 4D3, Purified

Product Data

• Clone Name: 4D3
• Application: ELISA, FC, IF, WB
• Recommended Dilution: ELISA.; Western blot (1/1,000-1/2,000). ; Flow Cytometry.; Immunofluorescence/Immunocytochemistry.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human BID (aa 1-195) purified from E. coli
• Specificity: The antibody recognizes Human BID.; Other species not tested.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: BH3 interacting domain death agonist
• Database Link:
  P55957
• Background: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases.
• Synonyms: p22 BID

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Pathways in cancer, Viral myocarditis