EPM2A Mouse Monoclonal Antibody [Clone ID: k2A3]
Specifications
| Product Data | |
| Clone Name | k2A3 |
|---|---|
| Application | ELISA, FC, ICC/IF, WB |
| Recommended Dilution | ELISA. Western blot (1/1,000-1/2,000). Flow Cytometry. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Immunogen | Recombinant human EPM2A (243-331aa) purified from E. coli |
| Specificity | The antibody recognizes EPM2A. |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purification | By protein-G affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| Database Link | |
| Background | Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules. Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2 (EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy. |
| Synonyms | Laforin isoform a,epilepsy, progressive myoclonus type 2A Lafora disease (laforin), epilepsy progressive myoclonus type 2 Lafora disease (laforin), LDE, LD |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
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