STEAP1 Mouse Monoclonal Antibody [Clone ID: J2D2]
Product Data | |
Clone Name | J2D2 |
---|---|
Application | ELISA, IF, IHC, WB |
Recommended Dilution | ELISA. Western blot: 1/1000-1/2000. Immunofluorescence: 1/100-1/300. Immunohistochemsitry on Praffin Sections: 1/50-1/100. |
Reactivity | Human, Rat |
Antibody Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Recombinant Human STEAP1 (1-70 aa) purified from E. coli |
Specificity | The antibody recognizes STEAP1. |
Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | six transmembrane epithelial antigen of the prostate 1 |
Database Link | |
Background | Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. NCBI Accession No: NP_036581 |
Synonyms | STEAP-1, Metalloreductase STEAP1, PRSS24 |
Reference Data |
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