ICAM1 Mouse Monoclonal Antibody [Clone ID: MEM-111]

SKU AM08311PU-N

ICAM1 mouse monoclonal antibody, clone MEM-111, Purified

Product Data

• Clone Name: MEM-111
• Application: ELISA, FC, IHC, WB
• Recommended Dilution: ELISA.; Flow Cytometry.; Immunohistochemistry on Paraffin Sections: 10 µg/ml.; Western Blot.
• Reactivity: Bovine, Human, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Raji Human Burkitt's lymphoma cell line.
• Specificity: AM08311PU-N with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.
• Buffer: PBS, pH 7.4 containing 15 mM Sodium Azide as preservative.; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein A Chromatography.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: intercellular adhesion molecule 1
• Database Link:
  P05362
• Background: ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
• Synonyms: ICAM-1

Reference Data