Lamp1 Rat Monoclonal Antibody [Clone ID: 1D4B]

SKU AM08087AC-N

Lamp1 rat monoclonal antibody, clone 1D4B, APC

Product Data

• Clone Name: 1D4B
• Application: FC
• Recommended Dilution: Flow Cytometry: < / = 0.2 µg/10e6 cells. (Ref.5)
• Reactivity: Mouse
• Antibody Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Plasma membrane fraction of mouse embryo NIH3T3 cell line. (Ref.1)
• Specificity: This antibody is specific to CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa).
• Buffer: PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent; Label: APC; State: Liquid purified Ig fraction.; Label: Allophycocyanin
• Concentration: lot specific
• Conjugation: APC
• Storage: Store the antibody undiluted at 2-8°C.; DO NOT FREEZE!; This product is photosensitive and should be protected from light.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: lysosomal-associated membrane protein 1
• Database Link:
  P11438
• Background: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. (Ref.2); CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.3); LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. (Ref.4)
• Synonyms: LAMP-1, LAMPA, LGP120

Reference Data