Ctla4 Hamster Monoclonal Antibody [Clone ID: 1B8]

SKU AM08060FC-N

Ctla4 hamster monoclonal antibody, clone 1B8, FITC

Product Data

• Clone Name: 1B8
• Application: FC
• Recommended Dilution: Flow Cytometry: < / = 3 µg/10e6 cells. (Ref.1,2)
• Reactivity: Mouse
• Antibody Host: Hamster
• Isotype: IgG
• Clonality: Monoclonal
• Specificity: This Monoclonal antibody is specific to CD152/CTLA-4.
• Buffer: PBS containing 0.09% Sodium Azide as preservative.; Label: FITC; State: Liquid purified Ig fraction.; Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.; This product is photosensitive and should be protected from light.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: cytotoxic T-lymphocyte-associated protein 4
• Database Link:
  P09793
• Background: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (Ref.1-4) However CD152 is thought to be a negative regulator of T cell activation (Ref.1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer (Ref.1), and is relatively conserved among Humans, Mice and Chickens. (Ref.2)
• Synonyms: CTLA-4

Reference Data