Ly6c1 Rat Monoclonal Antibody [Clone ID: HK1.4]
Product Data | |
Clone Name | HK1.4 |
---|---|
Application | FC |
Recommended Dilution | Flow Cytometry: purified antibody < / = 1 µg/10e6 cells FITC, BIOT, and AF488 conjugates < / = 1 µg/10e6 cells PACBLU conjugate < / = 0.3 µg/10e6 cells PE conjugate < / = 0.2 µg/10e6 cells AF647 and AF700 conjugates < / = 0.1 µg/10e6 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 µL. |
Reactivity | Mouse |
Antibody Host | Rat |
Isotype | IgG2c |
Clonality | Monoclonal |
Specificity | This antibody is specific to Murine Ly-6C (Mr. 18 kDa) |
Buffer | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | lymphocyte antigen 6 complex, locus C1 |
Database Link | |
Background | Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells, while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes. |
Synonyms | Lymphocyte antigen 6C2, Ly-6C2, Ly6C2, Mouse Macrophage Marker |
Reference Data |
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