Glypican 3 (GPC3) Mouse Monoclonal Antibody [Clone ID: 9C2]
Product Data | |
Clone Name | 9C2 |
---|---|
Application | ELISA, FC, IF, IHC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivity | Human, Mouse |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human GPC3 expressed in E. Coli. |
Specificity | Recognizes Glypican-3 / GPC3. |
Buffer | PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 0.5% protein Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 65.5 kDa |
Gene Name | glypican 3 |
Database Link | |
Background | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. |
Synonyms | Intestinal protein OCI-5, GTR2-2, MXR7, OCI5 |
Reference Data |
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