COTL1 Mouse Monoclonal Antibody [Clone ID: 5C8]

SKU AM06725PU-N

COTL1 mouse monoclonal antibody, clone 5C8, Purified

Product Data

• Clone Name: 5C8
• Application: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000. ; Western Blot: 1/500 - 1/2000.; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human COTL1 expressed in E. Coli.
• Specificity: Recognizes Coactosin-like protein (COLT1).
• Buffer: PBS; State: Purified; State: Liquid purified antibody; Stabilizer: 0.5% protein stabilizer; Preservative: 0.05% Sodium Azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 16 kDa
• Gene Name: coactosin like F-actin binding protein 1
• Database Link:
  Q14019
• Background: This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
• Synonyms: COTL1, CLP
• Note:

  Tissue Array Results; Colon cancer, Rectal cancer, Hepatic Carcinoma, Liver cancer, Renal cell Carcinoma, Kidney, Prostate cancer, Lung cancer, Breast cancer, Ovarian cancer, Endometrial cancer, Cervical cancer, Bladder cancer, Myocardial.

Reference Data