Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone ID: 2G10]

SKU AM06717PU-N

Neurofilament (NEFL) mouse monoclonal antibody, clone 2G10, Purified

Product Data

• Clone Name: 2G10
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.; Immunohistochemistry on paraffin sections: 1/200 - 1/1000.; Immunofluorescence: 1/200 - 1/1000.; Flow cytometry: 1/200 - 1/400.; ELISA: 1/10000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human NEFL expressed in E. Coli.
• Specificity: This antibody reacts to NEFL.
• Buffer: PBS; State: Purified; State: Liquid purified Ig fraction; Stabilizer: 0,5% BSA; Preservative: 0.05% sodium azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 62 kDa
• Gene Name: neurofilament, light polypeptide
• Database Link:
  P07196
• Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
• Synonyms: NF-L,NEFL, NF68, 68 kDa neurofilament protein

Reference Data