MEKK2 (MAP3K2) Mouse Monoclonal Antibody [Clone ID: 4B4]
Specifications
| Product Data | |
| Clone Name | 4B4 |
|---|---|
| Application | ELISA, IF, WB |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of human MAP3K2 expressed in E. Coli. |
| Specificity | This antibody reacts to MAP3K2. |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 70 kDa |
| Gene Name | mitogen-activated protein kinase kinase kinase 2 |
| Database Link | |
| Background | The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. |
| Synonyms | MAPKKK2, MEKK2 |
| Reference Data | |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins |
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