Prohibitin (PHB) Mouse Monoclonal Antibody [Clone ID: 5H7]

SKU AM06675SU-N

Prohibitin (PHB) mouse monoclonal antibody, clone 5H7, Ascites

Product Data

• Clone Name: 5H7
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.; Immunohistochemistry on paraffin sections: 1/200 - 1/1000.; Immunofluorescence: 1/200 - 1/1000.; Flow cytometry: 1/200 - 1/400.; ELISA: 1/10000.
• Reactivity: Human, Monkey, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human PHB expressed in E. Coli.
• Specificity: This antibody reacts to PHB.
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 30 kDa
• Gene Name: prohibitin
• Database Link:
  P35232
• Background: Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
• Synonyms: PHB1

Reference Data