ERK1 (MAPK3) Mouse Monoclonal Antibody [Clone ID: 1E5]
Product Data | |
Clone Name | 1E5 |
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Application | ELISA, FC, IF, IHC, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
Reactivity | Human, Monkey, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human MAPK3 expressed in E. Coli. |
Specificity | This antibody reacts to MAPK3. |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 44 kDa |
Gene Name | mitogen-activated protein kinase 3 |
Database Link | |
Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. |
Synonyms | MAP kinase 3, MAPK 3, ERK-1, ERT2, p44-MAPK, p44-ERK1, PRKM3 |
Reference Data |
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