ABCG2 Mouse Monoclonal Antibody [Clone ID: 3G8]

SKU AM06628SU-N

ABCG2 mouse monoclonal antibody, clone 3G8, Ascites

Product Data

• Clone Name: 3G8
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/2000.; Immunohistochemistry on Paraffin Sections: 1/200-1/1000.; Immunofluorescence: 1/200-1/1000.; Flow Cytometry: 1/200-1/400.; ELISA: 1/10000.
• Reactivity: Human, Monkey, Mouse
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human ABCG2 expressed in E. Coli.
• Specificity: This antibody reacts to ABCG2.
• Buffer: State: Ascites; State: Ascitic fluid; Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 72 kDa
• Gene Name: ATP binding cassette subfamily G member 2 (Junior blood group)
• Database Link:
  Q9UNQ0
• Background: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.
• Synonyms: Breast cancer resistance protein 1, ABCP, MXR

Reference Data