ABCG2 Mouse Monoclonal Antibody [Clone ID: 3G8]
Specifications
| Product Data | |
| Clone Name | 3G8 |
|---|---|
| Application | ELISA, FC, IF, IHC, WB |
| Recommended Dilution | Western Blot: 1/500-1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000. Immunofluorescence: 1/200-1/1000. Flow Cytometry: 1/200-1/400. ELISA: 1/10000. |
| Reactivity | Human, Monkey, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of human ABCG2 expressed in E. Coli. |
| Specificity | This antibody reacts to ABCG2. |
| Buffer | State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 72 kDa |
| Gene Name | ATP binding cassette subfamily G member 2 (Junior blood group) |
| Database Link | |
| Background | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon. |
| Synonyms | Breast cancer resistance protein 1, ABCP, MXR |
| Reference Data | |
| Protein Categories | CD Markers, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.