Interleukin 34 (IL34) Mouse Monoclonal Antibody [Clone ID: 1D12]

SKU AM06478SU-N

Interleukin 34 (IL34) mouse monoclonal antibody, clone 1D12, Ascites

Product Data

• Clone Name: 1D12
• Application: FC, IF, WB
• Recommended Dilution: ELISA: 1/10000.; Western Blot: 1/500 - 1/2000.; Immunofluorescence: 1/200 - 1/1000.; Flow Cytometry: 1/200 - 1/400.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human IL34 expressed in E. Coli.
• Specificity: Recognizes Interleukin-34 / IL34
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 27.5 kDa
• Gene Name: interleukin 34
• Database Link:
  Q6ZMJ4
• Background: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.
• Synonyms: IL-34, C16orf77

Reference Data