VEGF Receptor 2 (KDR) Mouse Monoclonal Antibody [Clone ID: 4B4]

SKU AM06371SU-N

VEGF Receptor 2 (KDR) mouse monoclonal antibody, clone 4B4, Ascites

Product Data

• Clone Name: 4B4
• Application: ELISA, FC, IF, WB
• Recommended Dilution: Western blot: 1/500-1/2000.; Immunofluorescence: 1/200-1/1000.; Flow Cytometry: 1/200-1/400.; ELISA: 1/10000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant extracellular fragment of human VEGFR-2 / KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.
• Specificity: This antibody recognizes Human VEGFR-2 / KDR. ; Other species not tested.
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 152 kDa
• Gene Name: kinase insert domain receptor
• Database Link:
  P35968
• Background: KDR has also been designated as VEGFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk-1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
• Synonyms: VEGFR2, FLK1, KDR, VEGF Receptor 2

Reference Data