CD44 Mouse Monoclonal Antibody [Clone ID: 8E2F3]
Product Data | |
Clone Name | 8E2F3 |
---|---|
Application | ELISA, FC, IF, IHC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. Flow Cytometry: 1/200-1/400. Immunohistochemistry on Paraffin Sections: 1/200-1/1000. |
Reactivity | Human, Mouse |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human CD44 (628-699) expressed in E. Coli. |
Specificity | Recognizes CD44 |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 82 kDa |
Gene Name | CD44 molecule (Indian blood group) |
Database Link | |
Background | CD44, also known as IN, LHRMIC4, CDW44, HCELL is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. |
Synonyms | LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1 |
Reference Data |
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