Lin28 (LIN28A) Mouse Monoclonal Antibody [Clone ID: 6D1F9]
Specifications
| Product Data | |
| Clone Name | 6D1F9 |
|---|---|
| Application | ELISA, IF, WB |
| Recommended Dilution | ELISA: 1/10000. Western Bloting: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli. |
| Specificity | Recognizes LIN28 |
| Buffer | 0.01M Phosphate buffer, pH 7.4 State: Aff - Purified State: Liquid purified IgG fraction Preservative: 0.03% Sodium Azide |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | lin-28 homolog A |
| Database Link | |
| Background | Lin-28 homolog (C. elegans), also known as LIN28, CSDD1, ZCCHC1 (NP_078950) was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation. |
| Synonyms | LIN-28, LIN28A, CSDD1, ZCCHC1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
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