MDMX (MDM4) Mouse Monoclonal Antibody [Clone ID: 2D10F4]

SKU AM06258SU-N

MDMX (MDM4) mouse monoclonal antibody, clone 2D10F4, Ascites

Product Data

• Clone Name: 2D10F4
• Application: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/10000. ; Western Blot: 1/500 - 1/2000. ; Immunofluorescence: 1/200 - 1/1000.; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human MDM4 expressed in E. Coli.
• Specificity: Recognizes MDM4
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 55 kDa
• Gene Name: MDM4, p53 regulator
• Database Link:
  O15151
• Background: MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.
• Synonyms: MDMX, MDM-4

Reference Data